35822 - CHARACTERISTICS AND OUTCOMES OF PREGNANT WOMEN WITH SARS-COV-2 IN BRAZIL - JAN TO NOV 2020
LISIANE F. LEAL - DEPARTMENT OF EPIDEMIOLOGY, BIOSTATISTICS, AND OCCUPATIONAL HEALTH, MCGILL UNIVERSITY, MONTREAL, CANADA, JOANNA MERCKX - DEPARTMENT OF EPIDEMIOLOGY, BIOSTATISTICS AND OCCUPATIONAL HEALTH, MCGILL UNIVERSITY, MONTREAL, CANADA, DESHAYNE B. FELL - SCHOOL OF EPIDEMIOLOGY AND PUBLIC HEALTH, UNIVERSITY OF OTTAWA, OTTAWA, CANADA, RICARDO DE S. KUCHENBECKER - FACULDADE DE MEDICINA, UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL, PORTO ALEGRE, BRASIL., ANGELICA E. MIRANDA - DEPARTAMENTO DE MEDICINA SOCIAL, UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO, VITÓRIA, BRASIL, WANDERSON K. DE OLIVEIRA, ROBERT WILLIAM PLATT - DEPARTMENT OF EPIDEMIOLOGY, BIOSTATISTICS, AND OCCUPATIONAL HEALTH, MCGILL UNIVERSITY, MONTREAL, CANADA, LÍVIA ANTUNES - INSTITUTO BRASILEIRO DE DESENVOLVIMENTO E SUSTENTABILIDADE, IABS, MARIÂNGELA F. SILVEIRA - PROGRAMA DE PÓS-GRADUAÇÃO EM EPIDEMIOLOGIA, FACULDADE DE MEDICINA, UNIVERSIDADE FEDERAL DE PELOTAS, PELOTAS, BRAZIL, NATÁLIA BORDIN BARBIERI - PROGRAMAS DAS NAÇÕES UNIDAS PARA O DESENVOLVIMENTO NO BRASIL, PNUD BRASIL, BRASIL.
Objectives: Evaluate characteristics, symptoms, and outcomes of pregnant women by SARI type and region.
Methods: Currently and recently pregnant women aged 10-49 years hospitalized for severe acute respiratory infection (SARI) from January through November 2020 were selected. SARI cases were grouped into: COVID-19; influenza or other detected agent SARI; and SARI of unknown etiology. Characteristics, symptoms, and outcomes were presented by SARI type and region. We used descriptive statistics to profile the study population. Binomial proportion and 95% confidence intervals (95% CI) for outcomes were obtained using the Clopper-Pearson method.
Results and conclusions: Of 945,460 hospitalized SARI cases in the SIVEP-Gripe, we selected 11,074 women aged 10-49 who were pregnant (7,964) or recently pregnant (3,110). COVID-19 was confirmed in 49•4% cases; 1•7% had influenza or another etiological agent, and 48.9% had SARI of unknown etiology. The pardo race/ethnic group accounted for 50% of SARI cases. Hypertension/Other cardiovascular diseases, chronic respiratory diseases, diabetes, and obesity were the most common comorbidities. A total of 362 women with COVID-19 (6.6%; 95%CI 6.0-7.3) died. Mortality was 4•7% (2•2-8•8) among influenza patients and 3.3% (2.9-3.8) among those with SARI of unknown etiology. The South-East, Northeast, and North regions recorded the highest frequencies of mortality among COVID-19 patients. Mortality among pregnant and recently pregnant women with SARIs was elevated among those with COVID-19, particularly in regions where maternal mortality is already high
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